A Pennsylvania woman was killed while cleaning the cage of an American black bear. Her children and others summoned a neighbor, who shot the bear to death, but the woman had already been mortally wounded. The woman and her husband apparently kept various exotic animals. Several news stories mention a Bengal tiger and a lion. Another mentions that they kept a jaguar and other exotic cats in the past, though it's not clear whether these are still on the premises.
[Thanks to Steve V. for the tip.]